We are looking for a talented and driven R&D Chemist to join our team. The successful candidate will be responsible for developing and optimizing chemical processes for synthesizing active pharmaceutical ingredients (APIs). This role requires a strong background in synthetic organic chemistry, process development, and scale-up techniques. The R&D Chemist will collaborate with cross-functional teams to ensure the smooth transition of processes from the lab to full-scale production.
Key Responsibilities: Process Development: • Conduct research and design experiments to develop and optimize synthetic routes for API molecules. • Perform literature searches for identified API molecules to determine synthesis routes, polymorphs, and analytical methods. • Conduct experimental trials to assess feasibility and optimize designed synthetic routes for API molecules. Documentation: • Record all experiments in the laboratory notebook (LNB) and maintain corresponding analytical data in organized folders. • Design synthetic routes for the synthesis and isolation of impurities and reference standards. • Ensure all documentation meets Good Manufacturing Practices (GMP) and regulatory standards. Safety and Compliance: • Adhere to all safety protocols and ensure a safe working environment in the laboratory. • Develop non-infringing synthetic processes based on literature, raw material availability, and polymorph studies. • Stay up-to-date with industry trends, regulatory guidelines, and advancements in chemical synthesis and analytical techniques. Team Collaboration: • Plan daily activities for team members, focusing on feasibility studies, process optimization, and laboratory validation. • Work closely with the Analytical Research and Development (ARD) team on method development, in-process testing, and reference standards qualification. Qualifications: • Education: MSc/BSc in Organic Chemistry, • Experience: Minimum of 3-5 years of experience in process development and optimization in the pharmaceutical or bulk drug industry. • Skills: o Strong knowledge of synthetic organic chemistry and process chemistry. o Proficiency in using and interpreting data from analytical instruments. o Excellent problem-solving skills and attention to detail. o EZective communication and teamwork skills. o Ability to work independently and manage multiple projects simultaneously
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